Reddy noted that intensifying therapy, whether anti-inflammatory agents, antivirals or a combination, should be considered in patients who present to the hospital with COVID-19 and an atrial arrhythmia. “We believe that this worsened outcome with AF in these patients is probably not related to a direct myocardial effect of the viral disease state but rather the generalized inflammatory situation,” Reddy told Healio.
The take-home message from the study is that a patient who is hospitalized with COVID-19 or influenza and develops AF is at very high risk, Reddy said in an interview. Presence of AF or atrial flutter correlated with worsened mortality in both the COVID-19 cohort (RR = 1.77) and the influenza cohort (RR = 1.78), Reddy and colleagues wrote. 93), the researchers wrote, though noting the absolute in-hospital mortality rate was lower in the influenza cohort than in the COVID-19 cohort (9% vs. 03) and the rate of new-onset AF or atrial flutter was 4% ( P vs. 1, 2020 (mean age, 66 years 42% men), the rate of AF or atrial flutter was 12% ( P vs. 01) compared with those without new-onset AF or atrial flutter, according to the researchers.Īmong 1,420 patients with influenza hospitalized from 2017 to Jan. 01) and had higher rates of mortality (46% vs. A malfunction in the electrical system of the heart makes the upper chambers of the heart (called the atria) beat so quickly that they twitch or skip beats. AFib is a condition characterized by a disrupted heartbeat. 01), had more myocardial injury as assessed by troponin I (0.2 ng/mL vs. A feeling of fluttering in the chest is the classic symptom of atrial fibrillation or AFib.
#Flutter in chest manual
4 to Ap(mean age, 66 years 59% men), 10% had AF or atrial flutter, and among those who had no history of atrial arrhythmias, 4% had AF or atrial flutter, the researchers wrote, noting that in a manual review of 1,110 patients, the incidence rate of AF or atrial flutter was 13%.Īmong those with COVID-19, patients with new-onset AF or atrial flutter were older, had increased inflammatory markers, including interleukin-6 (93 pg/mL vs. The fact that it occurs in both COVID and influenza is more consistent with the mechanism of worse outcomes being more from the generalized poor inflammatory state than being something very specific to COVID,” Reddy told Healio.Īmong 3,970 patients with COVID-19 admitted to Mount Sinai system hospitals from Feb. “From a relative perspective, AF seems be a significant independent negative biomarker that predicts mortality. Reddy said the researchers found that AF was also occurring in patients with influenza and contributed to an increase in their mortality. Helmsley Charitable Trust Professor of Medicine in Cardiac Electrophysiology at Icahn School of Medicine at Mount Sinai, told Healio. Reddy, MD, director of cardiac arrhythmia services for The Mount Sinai Hospital and the Mount Sinai Health System and the Leona M. One of the ways to try and look at this was to see if another severe respiratory illness, not COVID, affected people and increased their atrial fibrillation and mortality,” Vivek Y. “When we started out, it wasn’t clear whether or not the SARS-CoV-2 virus actually had a direct effect on the myocardium, causing arrhythmias.
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